Stem cells reverse stroke damage and restore movement in mice
ScienceDaily
Stem cells reverse stroke damage and restore movement in mice
Stem cell transplants helped regenerate stroke-damaged brain tissue in mice, producing new neurons and restoring lost motor function. The treatment also improved blood vessels, inflammation, and the blood-brain barrier, raising hopes that a similar approach could eventually help repair the human brain after stroke.
Is there some kind of interview to find a mouse that suffered from stroke?
Actually, I maybe don’t want to know the reality
They probably induce it then treat it to see what happens
Biotech companies breed mice for specific models. It wouldn’t surprise me to learn that they offer a mouse that has high probability to stroke.
Or just they just use magnets apparently (How do they work?)
cri.utsw.edu/ge-lab-has-developed-a-groundbreakin…
No. They block the carotid artery.
Niccccee
Any progress in stroke research is helpful. After seeing the aftermath of a couple family members having strokes, to say it’s life changing isn’t adequate. Truly terrible.
Actual article, dated Sep-2025.
A lot of money being wasted to find cures for mice. Maybe they should work on finding cures for people instead.
I spent a career in research and I can tell you that mice are excellent models for discovery, AMA
Why does my left bollock look like jackfruit suddenly?
According to Freud, because your mum had a face like a jackfruit and you’re secretly lusting for her.
Not really. What’s the translate rate to humans? 9%?
Mice can model some diseases well, but they are not universally good models.
Not universal, for example we use zebrafish for spine defect models since mouse spine has an odd curve/hunch that doesn’t line up as well. But for general metabolism/pathology/embryonic development they do a great job of mimicking human disease under the microscope. Its not always 1:1 but we learn a lot from these little guys.
Do you volunteer to have a stroke induced so researchers then can test their treatment?
they come to clinic every hour in a big city.
I always thought that the /s was a stupid thing, but judging from the down votes on your comment, I guess it’s a necessity
They have a point. Mouse model research translation to human disease has a poor track record. Mouse model labs spin in circles between models and never try to translate into humans. Some diseases stall for decades in models.
The mouse’s brain plasticity is orders of magnitude higher than a human’s.
I have seen many people hold this opinion unironically.
Yes, this research would move so much faster if we simply induced strokes in people and injected them with stuff to see what happens… /s
I think tpihkal just volunteered
related research:
scmp.com/…/chinese-drug-loberamisal-extends-strok…
Chinese drug loberamisal extends stroke treatment window from 6 hours to 2 days
“The large-scale multicentre phase 3 trial found that 70 per cent of patients who received loberamisal intravenously within two days of a stroke regained complete functional independence – an increase of 13 percentage points over standard care alone.”
Nice, still waiting for teeth regrowth, colonoscopy not involving fingers up my ass or a diet drug available for me tho. Feels like this shit wont hit market until the planet has been literally cooked.
There is. Eat more fibers and veggies.
And by then it’ll only be available for the rich.
You can already poop in a box and mail it off instead of fingers up the ass. – www.cologuard.com
GLP-1 is already a diet drug that’s available to most people.
2/3 of your hopes already exist. Maybe not for everyone, maybe it’s out of your price range, but they exist.
GLPs are coming down in price, I’ve seen them as low as $130/mo. I lost 20 pounds in the first three weeks. Its slowed to about 1-2 per week now but it is steady.
If they can perfect the saftey switch they talk about in the article. Then maybe stem cells for the brain will be like vitamins. Cause damage to like the blood brain barrier is hard to detect, but seems to be present in a decent number of “syndromes”. Like autism for one. It would be nice if they understood the why and how’s, but that could be decades away.